Peroxidase, Horseradish is an archetypal haem-containing enzyme that uses hydrogen peroxide or alkyl peroxides to catalyze oxidative reactions, including the hydroxylation and polymerization of aromatic compounds. It is commonly used as a detection enzyme in biochemical assays like ELISA, Western blotting, and immunohistochemistry, due to its ability to produce strong colorimetric or chemiluminescent signals for […]

EGNHS (EGS crosslinker) is a proteolytic targeting chimera (PROTAC) linker belonging to the alkyl/ether class, used in the synthesis of PROTAC molecules. It can form a cross-link between Lys232 and Lys241 of horseradish peroxidase C (HRP) and modify Lys174 without cross-linking.

c-di-AMP (Cyclic diadenylate) is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP (Cyclic diadenylate) is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune […]

SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

Sacubitril is a potent and orally active inhibitor of NEP (neprilysin) with an IC50 of 5 nM. It exhibits the potential to treat chronic heart failure with reduced ejection fraction.

5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.

Hydroxyphenyllactic acid is an antifungal metabolite.

Ponceau 4R is a synthetic colorant that can be used for food coloring. Ponceau 4R is a strawberry red azo dye that can be used in a variety of foods, usually synthesized from aromatic hydrocarbons, and is stable to light, heat, and acids.

NBD-Cl is a nonfluorescent reagent which becomes highly fluorescent after reaction with thiol or amino groups.

N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water.