5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm.

Ceftriaxone is a long-acting, broad-spectrum β-lactam, third-generation semisynthetic cephalosporin with broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and some anaerobic bacteria. It also acts as a covalent inhibitor of GSK3β with an IC50 of 0.78 μM after 60 minutes of preincubation with the enzyme in vitro.

Transferrin is a glycoprotein that plays a crucial role in iron transport in the bloodstream. It binds ferric ions (Fe³⁺), forming a stable complex that is transported to cells through transferrin receptors (CD71) on the cell membrane. By maintaining cellular iron balance, transferrin helps protect against apoptosis, especially during iron deficiency. Transferrin levels and receptor […]

Ceramides Mixture are endogenous long chain, bioactive lipids forming the hydrophobic backbone of complex sphingolipids and are major constituents of the stratum corneum, contributing to the skin’s permeability barrier. They regulate key biological processes such as growth inhibition, cell cycle arrest, telomerase activity modulation, proliferation, apoptosis, and senescence.

Cyclosporin H is a selective and potent inhibitor of FPR-1 (formyl peptide receptor 1). Cyclosporin H, a viral transduction enhancer, increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). Cyclosporin H displays an additive effect when combined with Rapamycin or Prostaglandin E2. Cyclosporin H lacks immunosuppressant activity of […]

N-Acetyl-D-cysteine is a derivative of cysteine with antioxidant properties. It shares some properties with N-acetyl-L-cysteine, such as ROS scavenging due to its thiol group, but it cannot participate in glutathione biosynthesis.

Docetaxal (10-Acetyl docetaxel) is an analog of Docetaxel (HY-B0011), with anticancer activity. Docetaxel is a microtubule disassembly inhibitor, with antimitotic activity.

Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes.

Win 18446 is a bisdichloroacetyldiamines that inhibits ALDH1a2 enzyme activity in vitro with an IC50 of 0.3 μM. It also reversibly suppresses spermatogenesis by inhibiting testicular retinoic acid biosynthesis mediated by ALDH1A2.

Peroxidase, Horseradish is an archetypal haem-containing enzyme that uses hydrogen peroxide or alkyl peroxides to catalyze oxidative reactions, including the hydroxylation and polymerization of aromatic compounds. It is commonly used as a detection enzyme in biochemical assays like ELISA, Western blotting, and immunohistochemistry, due to its ability to produce strong colorimetric or chemiluminescent signals for […]