Diallyl Trisulfide is an orally active anticancer agent that can be isolated from garlic. Diallyl Trisulfide has the ability to induce apoptosis and exhibits anticancer, anti-inflammatory, antioxidant, and antibacterial activities. Diallyl Trisulfide can be used to study a variety of cancers, including liver, colon and prostate cancer.

GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively.

Tetrac (Tetraiodothyroacetic acid), a derivative of L-thyroxine (T4), is a thyrointegrin receptor antagonist. Tetrac blocks the actions of T4 and 3,5,3′-triiodo-L-thyronine (T3) at the cell surface receptor for thyroid hormone on integrin αvβ3. Tetra has anti-angiogenic and anti-tumor activities.

Aureobasidin A (Basifungin) is a cyclic peptide antibiotic with oral activity. Aureobasidin A is an inhibitor of inositol phosphorylated ceramide synthetase AUR1. Aureobasidin A has antifungal and antiparasitic activity.

Cholecystokinin Octapeptide, desulfated, (CCK-8 (desulphated)) is a synthetic peptide lacking the sulfate group on its tyrosine residue, reducing its activity at CCK-A receptors while allowing selective binding to CCK-B receptors. It is used in research to study central and gastric effects mediated by CCK-B receptors, independent of digestive enzyme stimulation.

α-CGRP(human) (Calcitonin gene-related peptide) is a regulatory neuropeptide of 37 amino acids, widely distributed in the central and peripheral nervous system, predominantly in cell bodies of the dorsal root ganglion (DRG) with potent vasodilatory, inotropic, and chronotropic effects. It is a reversible antagonist of the haemodynamic effects of human α-CGRF, and may holds potential as […]

Catalase, Aspergillus niger is a heme-containing antioxidant enzyme that decomposes hydrogen peroxide into water and oxygen. It plays a crucial role in regulating intracellular hydrogen peroxide levels and protecting cells from oxidative damage. This enzyme also exhibits exceptional stability under acidic and oxidative conditions.

TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis.

Ammonium bicarbonate is a bioactive chemical.

Complete Freund’s Adjuvant (CFA) is an immunogenic stimulus, containing microbial TLR ligands, a strong inducer of Th1-type immune responses and is commonly used to trigger autoimmune disease in rodents. Induction of experimental autoimmune myocarditis (EAM) requires CFA to be administered twice along with a myocarditogenic peptide to establish the proinflammatory environment essential for disease development.