PF429242 dihydrochloride is a reversible and competitive SREBP site 1 protease (S1P) inhibitor with an IC50 of 175 nM.

MRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively.

MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A.

Nicotinamide riboside is an orally active NAD(+) precursor essential for cellular energy and metabolic functions. It Supplementation increases NAD(+) levels, activating sirtuins like SIRT1 and SIRT3, which improve oxidative metabolism and provide protection against metabolic issues induced by a high-fat diet. It also helps to reduce cognitive decline in a transgenic mouse model of Alzheimer’s […]

GW3965 is a potent, selective liver X receptor (LXR) agonist with EC50s of 190 nM and 30 nM for hLXRα and hLXRβ, respectively.

Daunorubicin is an anthracycline antibiotic and a cell cycle–nonspecific chemotherapeutic agent that functions by inhibiting topoisomerase II and intercalating into DNA. It is primarily indicated for the treatment of acute lymphoblastic leukemia (ALL) and acute myelogenous leukemia (AML).

Cyclo(-RGDfK) is a cyclic peptides and a highly effective and selective Integrin αvβ3 inhibitor with an IC50 value of 0.94 nM. It specifically binds to the αvβ3 integrin on the cell surface, blocking integrin-mediated cell adhesion, migration and signal transduction processes, thereby inhibiting tumor angiogenesis and the invasion and metastasis of tumor cells.

Cy5-SE is a fluorescent dye speculated to label and bind with amine groups to form an irreversible covalent bond. It can be incorporated into chemo-photothermal therapeutic platform for eradicating the drug-resistant bacteria.

Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 72 nM.

2’3’-c-di-AM(PS)2 (Rp,Rp) ammonium salt (ADU-S100 ammonium salt), an activator of stimulator of interferon genes (STING), leads to potent and systemic tumor regression and immunity.