ZZM-1220 | MedChemExpress (MCE)
ZZM-1220 is a histone lysine methyltransferase G9a/GLP covalent inhibitor with IC50s of of 458 nM and 924 nM, respectively. ZZM-1220 inhibits H3K9me2 in cells and significantly induces apoptosis of triple-negative breast cancer (TNBC) cells and blocks the cell cycle in the G2/M phase[1].
| Trivial name | ZZM-1220 |
| Catalog Number | HY-156285 |
| Research Area | Cancer |
| Purity | ≥98.00% |
| SMILES | C=CC(NC1=CC(C2=NC3=CC(OC)=C(C=C3C(NC4CCN(CC4)C)=N2)OC)=CC=C1)=O |
| PubChem Chemical Structure ID | 169450111 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/zzm-1220.html |