ZX703 | MedChemExpress (MCE)

ZX703 (compound 5I) is a PROTAC that significantly degrades GPX4 in a dose- and time-dependent manner through the ubiquitin-proteasome and autophagy-lysosome pathways (DC₅₀=0.315 µM). ZX703 induces ferroptosis by inducing Reactive Oxygen Species (ROS) accumulation in cells. ZX703 can be used for cancer research^[1].

Price Not Available 1 mg ZX703 | MedChemExpress (MCE) Supplier Page

Trivial name	ZX703
Catalog Number	HY-157788
Research Area	Cancer
Purity	≥98.0%
SMILES	O=C([C@H]1N(C([C@@H](NC(CCCCCCCCCOC2=CC=C(C(C3=CC=C(Cl)C=C3)N4CCN(C(C5=NOC(C)=C5[N+]([O-])=O)=O)CC4)C=C2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC6=CC=C(C7=C(C)N=CS7)C=C6
Size	1 mg
Supplier Page	https://www.medchemexpress.com/zx703.html