UNC9036 | MedChemExpress (MCE)

UNC9036 is a PROTAC-based STING degrader, with a DC50 of 227 nM. UNC9036-mediated STING degradation is proteasome and VHL dependent (Srtucture Note: Red, STING agonist diABZI (HY-112921A); Blue, VHL ligand VH032 (HY-120217); Black, linker)[1].

Trivial name UNC9036
Catalog Number HY-158048
Research Area Inflammation/Immunology
Purity ≥98.0%
SMILES O=C(NCCCCCCCCC(N[C@@H](C(N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](C1)O)=O)C(C)(C)C)=O)C4=CC5=C(C(OC)=C4)N(C/C=C/CN6C(NC(C7=CC(C)=NN7CC)=O)=NC8=C6C(OCCCN9CCOCC9)=CC(C(N)=O)=C8)C(NC(C%10=CC(C)=NN%10CC)=O)=N5
Size 1 mg
Supplier Page https://www.medchemexpress.com/unc9036.html