Tubulin degrader 1 | MedChemExpress (MCE)

Tubulin degrader 1 (Compound 5i) is a BML284 (HY-19987) derivative that is an orally active colchicine-site noncovalent tubulin degradation agent with IC50 values ranging from 0.02 to 0.05 μM against the five tumor cell lines (Hela, HCT116, MCF-7, K562 and Molm-13). Tubulin degrader 1 has antiproliferative activity that effectively suppressed tumor growth[1].

Trivial name Tubulin degrader 1
Catalog Number HY-161324
Research Area Cancer
Purity ≥98.0%
SMILES COC1=CC=CC(C2=CC(NCC3=CC4=C(NC=C4)C=C3)=NC(N)=N2)=C1
Size 1 mg
Supplier Page https://www.medchemexpress.com/tubulin-degrader-1.html