Topoisomerase I inhibitor 14 | MedChemExpress (MCE)
Topoisomerase I inhibitor 14 (Compound 4h) is an inhibitor for Topoisomerase I. Topoisomerase I inhibitor 14 inhibits proliferation of A549 and C6 with IC50s of 4.56 μM and 13.17 μM, without significant toxicity in healthy cells NIH3T3 (IC50 is 74.44 μM), which exhibits anticancer potency[1].
| Trivial name | Topoisomerase I inhibitor 14 |
| Catalog Number | HY-162342 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | COC1=CC=C(C2=NC3=CC=C(C4=NN=C(SCC(N5CCN(C6=NC=CC=N6)CC5)=O)N4CC)C=C3N2)C=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/topoisomerase-i-inhibitor-14.html |