Thanatin TFA | MedChemExpress (MCE)
Thanatin TFA is an inducible cationic antimicrobial peptide. Thanatin TFA s a pathogen-inducible single-disulfide-bond-containing β-hairpin AMP. Thanatin TFA displays broad-spectrum activity against both Gram-negative and Gram-positive bacteria as well as against various species of fungi with MICs of 0.3-40 µM, 0.6-40 µM and 0.6-20 µM, respectively. Thanatin TFA has the property of competitive replacement of divalent cations from bacterial outer membrane (OM), leading to OM disruption[1][2].
| Trivial name | Thanatin TFA |
| Catalog Number | HY-P5601A |
| Research Area | Infection |
| Purity | ≥98.0% |
| SMILES | NCC(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@@H]4C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@]([H])([C@@H](C)O)C(NCC(N[C@@H](CCCCN)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCSC)C(O)=O)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CSSC4)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCC2)=O)C(C)C)=O)CCC1)=O)CCCCN)=O)CCCCN)=O)CO)=O.OC(C(F)(F)F)=O.[x] |
| Size | 5 mg |
| Supplier Page | https://www.medchemexpress.com/thanatin-tfa.html |