TGFβRI-IN-7 | MedChemExpress (MCE)

TGFβRI-IN-7 (Compound 2r) is a selective inhibitor of the TGFβ type II receptor (TGFβ RII) (IC50 = 4.1 μM). TGFβRI-IN-7 inhibits TGFβ signaling by promoting the proteolytic degradation of TGFβ RII. TGFβRI-IN-7 can block endothelial-to-mesenchymal transition and cell migration. TGFβRI-IN-7 can be used in cancer research[1].

Trivial name TGFβRI-IN-7
Catalog Number HY-161398
Research Area Cancer
Purity ≥98.0%
SMILES FC(F)(F)C1=CC=C(C2=CC=CC(CN(C)C(C3=CNC4=C3C(CC(C)(C)C4)=O)=O)=C2)C=C1
Size 1 mg
Supplier Page https://www.medchemexpress.com/tgfβri-in-7.html