Simvastatin acid-d9 ammonium | MedChemExpress (MCE)
Simvastatin acid-d9 ammonium is deuterated labeled Simvastatin acid ammonium (HY-119695A). Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2].
| Trivial name | Simvastatin acid-d9 ammonium |
| Catalog Number | HY-119695AS1 |
| Alternative Name(s) | Tenivastatin-d9 ammonium |
| Research Area | Inflammation/Immunology; Cardiovascular Disease |
| Purity | ≥98.0% |
| SMILES | C[C@@H]1C[C@H](OC([C@@]([2H])(C([2H])([2H])[2H])C([2H])([2H])C([2H])([2H])[2H])=O)[C@@]2([H])C(C=C[C@H](C)[C@@H]2CC[C@@H](O)C[C@@H](O)CC([O-])=O)=C1.[NH4+] |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/simvastatin-acid-d9-ammonium.html |