SIK-IN-3 | MedChemExpress (MCE)

SIK-IN-3 (Compound 6B) is an inhibitor for salt-inducible kinase (SIK), which inhibits SKI1, SIK2 and SIK3 with IC₅₀s of 0.1, 0.3 and 0.8 nM, respectively. SIK-IN-1 inhibits the release of TNFa with IC₅₀ of 0.6 nM, stimulates the LPS (HY-D1056) -induced IL-10 release with EC₅₀ of 3 nM in human macrophages^[1].

Price Not Available 1 mg SIK-IN-3 | MedChemExpress (MCE) Supplier Page

Trivial name	SIK-IN-3
Catalog Number	HY-161442
Research Area	Inflammation/Immunology
Purity	≥98.0%
SMILES	N#CC1=CC=CC2=NC=C(C3=CC(OC[C@]4(N)[C@@H](CC)CCC4)=C(C#N)C(SC)=C3)N21
Size	1 mg
Supplier Page	https://www.medchemexpress.com/sik-in-3.html