Rosuvastatin-13C,d3 sodium | MedChemExpress (MCE)
Rosuvastatin-13C,d3 sodium is 13C and deuterated labeled Rosuvastatin sodium (HY-17504B). Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM[2]. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels[1][2][3].
| Trivial name | Rosuvastatin-13C,d3 sodium |
| Catalog Number | HY-17504BS2 |
| Alternative Name(s) | ZD 4522-13C,d3 sodium; X-Plended-13C,d3 sodium; Crestor-13C,d3 sodium |
| Research Area | Metabolic Disease; Cardiovascular Disease |
| Purity | ≥98.0% |
| SMILES | O=C(O[Na])C[C@H](O)C[C@H](O)/C=C/C1=C(C(C)C)N=C(N([13C]([2H])([2H])[2H])S(=O)(C)=O)N=C1C2=CC=C(C=C2)F |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/rosuvastatin-13c-d3-sodium.html |