PTPN2/1-IN-3 | MedChemExpress (MCE)
PTPN2/1-IN-3 (compound 4) is a modified, orally active PTPN2/N1 inhibitor based on ABBV-CLS-484 (HY-145923). PTPN2/1-IN-3 has anti-tumor effects, inhibiting PTPN2 with an IC50 of 9.3 nM and having an oral bioavailability of 93% in mice.[4][1].
| Trivial name | PTPN2/1-IN-3 |
| Catalog Number | HY-162428 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | FC1=C(N2CC(NS2(=O)=O)=O)C(O)=CC3=C1CCN(CC)CC3 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/ptpn2-1-in-3.html |