PROTAC NAMPT Degrader-1 | MedChemExpress (MCE)

PROTAC NAMPT Degrader-1 is a potent PROTAC targeting NAMPT with aDC₅₀ value of 217 nM. PROTAC NAMPT Degrader-1 has anti-proliferative activity with an IC₅₀ value of 0.12μM against A2780 cells.
(Srtucture Note: PINK, NAMPT activator (HY-163445); Blue, VHL ligand (HY-163440); Black, linker)^[1].

Price Not Available 1 mg PROTAC NAMPT Degrader-1 | MedChemExpress (MCE) Supplier Page

Trivial name	PROTAC NAMPT Degrader-1
Catalog Number	HY-163440
Research Area	Cancer
Purity	≥98.0%
SMILES	O=C(NCC1=CC=NC=C1)NC2=CC=C(C=C2)S(=O)(N3CCN(CC3)C(C4=CC=C(C=C4)/N=N/C5=C(N(N=C5C)CCCCC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C=C7)C8=C(N=CS8)C)C)=O)=O)=O)C)=O)=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/protac-nampt-degrader-1.html