PROTAC CRBN ligand-2 | MedChemExpress (MCE)
PROTAC CRBN ligand-2 (12) is a Biguanide-PROTAC derivative, with an EC50 of 0.15 mM in KP4 cells. PROTAC CRBN ligand-2 (12) demonstrates the ability to alter levels of mitochondrial proteins, notably complexes I and IV[1].
| Trivial name | PROTAC CRBN ligand-2 |
| Catalog Number | HY-158152 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | N=C(NC(NCC1=CC=C(C=C1)C#CC2=CC=C(C=C2)NC(COC3=CC=CC4=C3C(N(C4=O)C5CCC(NC5=O)=O)=O)=O)=N)N.O=CO |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/protac-crbn-ligand-2.html |