PROTAC BTK Degrader-9 | MedChemExpress (MCE)

PROTAC BTK Degrader-9 (compound 23) is a PROTAC degrader that effectively targets BTK. PROTAC BTK Degrader-9 downregulates the BTK-PLCγ2-Ca²⁺-NFATc1 signaling pathway activated by RANKL. Thus, PROTAC BTK Degrader-9 was able to inhibit osteoclastogenesis and attenuate alveolar bone resorption in a mouse periodontitis model^[1].

Price Not Available 1 mg PROTAC BTK Degrader-9 | MedChemExpress (MCE) Supplier Page

Trivial name	PROTAC BTK Degrader-9
Catalog Number	HY-162280
Research Area	Cancer
Purity	≥98.0%
SMILES	CC1=CC(C2=NC(NC3=CN(C4CCN(CC4)CC5CCN(C6=CC=C7C(C(N(C7=O)C8C(NC(CC8)=O)=O)=O)=C6)CC5)N=C3)=NC=C2F)=CC=C1CNC(C9=CN(C(C)(C)C)N=N9)=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/protac-btk-degrader-9.html