pan-KRAS-IN-7 | MedChemExpress (MCE)
pan-KRAS-IN-7 (Compound 25) is an inhibitor for in human tumor mutated genes KRAS, which inhibits proliferation of KRAS mutated cells AsPC-1 (G12D mutant) and SW480 (G12V mutant) with IC50 of 0.35 and 0.51 nM, respectively[1].
Trivial name | pan-KRAS-IN-7 |
Catalog Number | HY-162440 |
Research Area | Cancer |
Purity | ≥98.0% |
SMILES | OC[C@@H]1N(CC#CC2=C[C@]([C@]3=C(CC(C)(C)COC4=O)C5=CC(C6=CSC(C[C@H](NC([C@H]7[C@H](C)[C@@H]7C)=O)C(N8CCC[C@@H]4N8)=O)=N6)=CC=C5N3CC)=C([C@H](C)OC)N=C2)CCOC1 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/pan-kras-in-7.html |