P-gp inhibitor 20 | MedChemExpress (MCE)

P-gp inhibitor 20 (compound H27) is a low cytotoxicity P-glycoprotein (P-gp) inhibitor. P-gp inhibitor 20 inhibits the efflux function of P-gp in a dose-dependent manner (without affecting the expression of P-gp), thereby reversing the multidrug resistance (MDR) of MCF-7/ADR cells, with an IC50 value of 46.6 nM. P-gp inhibitor 20 can be used for cancer research[1].

Trivial name P-gp inhibitor 20
Catalog Number HY-161260
Research Area Cancer
Purity ≥98.0%
SMILES O=C(C1=CC=CC([Se]C2=CNC3=CC=C(C4=CN(C)N=C4)C=C32)=C1)N5CCC6=CC(OC)=C(OC)C=C6C5
Size 1 mg
Supplier Page https://www.medchemexpress.com/p-gp-inhibitor-20.html