NB512 | MedChemExpress (MCE)
NB512 (compound 39a) is a dual inhibitor for BET and HDAC, which exhibits a efficient binding affinity with BRD4 bromodomains and HDAC1/2, with EC50s of 100-400 nM. NB512 exhibits an anti-proliferative activity towards cancer cells PaTu8988T and NMC[1].
| Trivial name | NB512 |
| Catalog Number | HY-163282 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | O=C(NC1=CC(C2=CC=CC=C2)=CC=C1N)C3=NC=C(C4=CN(C)C(C5=C4C=CN5)=O)C=C3 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/nb512.html |