Mutant IDH1/NAMPT-IN-1 | MedChemExpress (MCE)
Mutant IDH1/NAMPT-IN-1 (Compound 23h) is a dual inhibitor of mutant isocitrate dehydrogenase 1 (mutant IDH1) (IC50=14.93 nM) and nicotinamide phosphoribosyltransferase (NAMPT) (IC50=12.56 nM). Mutant IDH1/NAMPT-IN-1 can induce apoptosis. Mutant IDH1/NAMPT-IN-1 crosses the blood-brain barrier effectively[1].
| Trivial name | Mutant IDH1/NAMPT-IN-1 |
| Catalog Number | HY-158319 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | C[C@@H](C1=CC=C(C=C1)C2=CC=C(C=C2)NC(COC3=CC=CN=C3)=O)NC4=NC(N5[C@H](COC5=O)[C@H](C)F)=CC=N4 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/mutant-idh1-nampt-in-1.html |