MS8847 | MedChemExpress (MCE)

MS8847 is a highly potent EZH2 PROTAC degrader that recruits the E3 ligase von Hippel-Lindau (VHL). MS8847 potently degrades EZH2 in a ubiquitin-proteasome system-dependent manner. MS8847 effectively inhibits the growth of acute myeloid leukemia (AML) and triple-negative breast cancer (TNBC) cells^[1].

Price Not Available 1 mg MS8847 | MedChemExpress (MCE) Supplier Page

Trivial name	MS8847
Catalog Number	HY-162250
Research Area	Cancer
Purity	≥98.0%
SMILES	CC1=CC(C)=C(CNC(C2=C(C)C(N(C3CCOCC3)CC)=CC(C4=CC=C(CN5CCN(CCC(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](O)C6)=O)=O)=O)CC5)C=C4)=C2)=O)C(N1)=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/ms8847.html