MDMX/MDM2-IN-2 | MedChemExpress (MCE)
MDMX/MDM2-IN-2 is a potent p53-MDM2/MDMX dual inhibitors with Kis of 0.23 μM and 2.45 μM for MDM2 and MDMX, respectively. MDMX/MDM2-IN-2 inhibits the binding of p53 and MDM2 proteins. MDMX/MDM2-IN-2 restores the function of p53 and enables cell cycle arrest and apoptosis. MDMX/MDM2-IN-2 inhibits cell migration and invasion. MDMX/MDM2-IN-2 has antitumor activity[1].
| Trivial name | MDMX/MDM2-IN-2 |
| Catalog Number | HY-149250 |
| Research Area | Cancer |
| Purity | ≥98.00% |
| SMILES | O=C(C(N(C1=CC=C(C=C1)Cl)C(CCC(N2CCNCC2)=O)=O)C3=CC=C(C=C3Cl)F)C4=CC=C(C=C4)Cl |
| PubChem Chemical Structure ID | 168355523 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/mdmx-mdm2-in-2.html |