LEM-14-1189 | MedChemExpress (MCE)
LEM-14-1189, a LEM-14 (HY-114340) derivative, is a NSDs inhibitor with IC50s of 418 μM (NSD1), 111 μM (NSD2), and 60 μM (NSD3), respectively. The NSDs, histone lysine methyltransferases (HMTases), are oncoproteins, drivers of a number of tumors. LEM-14-1189 can be used for multiple myeloma (MM) research[1].
| Trivial name | LEM-14-1189 |
| Catalog Number | HY-125244 |
| Research Area | Cancer |
| Purity | ≥98.00% |
| SMILES | O=C(C(OC1=O)=CC2=C1C=CC=C2)NCCCN(CC3=NC4=C(C5=C(CCCC5)S4)C(N3)=O)CC6=NC7=C(C8=C(CCCC8)S7)C(N6)=O |
| PubChem Chemical Structure ID | 137796293 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lem-14-1189.html |