LEI-515 | MedChemExpress (MCE)
LEI-515 is a first-in-class peripherally restricted, reversible MAGL inhibitor. LEI-515 increases 2-AG levels in peripheral organs, but not mouse brain. LEI-515 attenuated liver necrosis, oxidative stress and inflammation in a CCl4-induced acute liver injury model[1].
| Trivial name | LEI-515 |
| Catalog Number | HY-163092 |
| Research Area | Inflammation/Immunology |
| Purity | ≥98.00% |
| SMILES | CCC(F)(C(CS(C1=C(C=C(C=C1)C(N2CCN([C@H]([C@@H]2C)C)C3=CC=CC(Cl)=C3)=O)Cl)=O)=O)F |
| PubChem Chemical Structure ID | 156760414 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lei-515.html |