KRB-456 | MedChemExpress (MCE)
KRB-456 is a small molecule that binds a dynamic allosteric binding pocket within the switch-I/II region of KRAS G12D. KRB-456 inhibits P-MEK, P-AKT, and P-S6 levels in vivo and inhibits the growth of cancer. KRB-456 can be used for the research of pancreatic cancer[1].
Trivial name | KRB-456 |
Catalog Number | HY-162112 |
Research Area | Cancer |
Purity | ≥98.00% |
SMILES | O[C@]12[C@@]([C@H](C(OC)=O)[C@@]34[C@@]2([H])CC[C@](CBr)(C(C4)=O)C3)([H])[C@@]5(C)C(C=C1C5=O)=O |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/krb-456.html |