KRAS G13D-IN-1 | MedChemExpress (MCE)

KRAS G13D-IN-1 (compound 41) is a selective and covalently reversible inhibitor of KRAS^G13D (IC₅₀: 0.41 nM). The selectivity for KRAS^G13D is 29-fold against KRAS wild type. KRAS G13D-IN-1 is an inhibitor of the GDP state and targets the SWII binding pocket of KRAS^G13D. KRAS G13D-IN-1 inhibits KRAS binding to GDP and turns on/off downstream signaling cascades^[1].

Price Not Available 1 mg KRAS G13D-IN-1 | MedChemExpress (MCE) Supplier Page

Trivial name	KRAS G13D-IN-1
Catalog Number	HY-161066
Research Area	Cancer
Purity	≥98.00%
SMILES	NC1=N[C@@]([C@@]2=C(F)C3=C(C(N4[C@@H](C)CN(C(/C=C/C5=CC=CC6=C5C[N@@]7C[C@H]6CC7)=O)CC4)=NC(OC[C@@]89CCCN8CC(C9)=C)=N3)C=C2Cl)=C(C(F)(F)F)C(C)=C1
Size	1 mg
Supplier Page	https://www.medchemexpress.com/kras-g13d-in-1.html