KGP591 | MedChemExpress (MCE)
KGP591 is a tubulin polymerization inhibitor (IC50 0.57 µM). KGP591 induces significant G2/M stagnation, inhibits cell migration, disrupts microtubule structure and cell morphology in MDA-MB-231 cells. KGP591 shows antitumor activity in orthotopic model of kidney cancer (RENCA)[1].
| Trivial name | KGP591 |
| Catalog Number | HY-155249 |
| Research Area | Cancer |
| Purity | ≥98.00% |
| SMILES | COC1=CC(C(C2=CNC3=CC(C4=CC=CC(O)=C4)=CC=C23)=O)=CC(OC)=C1OC |
| PubChem Chemical Structure ID | 168510364 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/kgp591.html |