KDM5B-IN-4 | MedChemExpress (MCE)
KDM5B-IN-4 (compound 11ad) is a lysine demethylase 5B (KDM5B) inhibitor with an IC50 of 0.025 μM KDM5B-IN-4 increases substrate H3K4me1/2/3 level by inhibiting KDM5B in PC-3 cells. KDM5B-IN-4 downregulates PI3K/AKT. KDM5B-IN-4 reduces tumor volume in mice and shows less toxic to organs[1].
| Trivial name | KDM5B-IN-4 |
| Catalog Number | HY-149091 |
| Research Area | Cancer |
| Purity | ≥98.00% |
| SMILES | CN1CCN(CC1)CCNC(C2=CC(C3=CC=C4C=CC=CC4=C3)=NC5=C2C=NN5C6=CC=CC=C6)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/kdm5b-in-4.html |