HER2-IN-17 | MedChemExpress (MCE)

HER2-IN-17 (Compound 2) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 <200 nM. HER2-IN-17 inhibits proliferation of HER2 YVMA mutated BaF3 cells with an IC50 <200 nM and amliorates non-small-cell lung cancer (NSCLC)[1].

Trivial name HER2-IN-17
Catalog Number HY-163418
Research Area Cancer
Purity ≥98.0%
SMILES C=CC(N1CC(C1)N2C=C(C=N2)C3=C4C(NC5=CC=C(C(C)=C5)OC6=CC7=NC=NN7C=C6)=NC=NN4C=C3)=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/her2-in-17.html