HER2-IN-15 | MedChemExpress (MCE)

HER2-IN-15 (Compound 1) is an inhibitor for HER2, which inhibits the Her YVMA exon 20 insertion mutation (HER2 YVMA) with an IC50 <200 nM. HER2-IN-15 inhibits proliferation of HER2 YVMA mutated BaF3 cells with an IC50 <200 nM and amliorates non-small-cell lung cancer (NSCLC)[1].

Trivial name HER2-IN-15
Catalog Number HY-163417
Research Area Cancer
Purity ≥98.0%
SMILES CC1=CC(NC2=NC=NN3C=CC(C4CN(C4)C(/C=C/CN(C)C)=O)=C23)=CC=C1OC5=CC6=NC=NN6C=C5
Size 1 mg
Supplier Page https://www.medchemexpress.com/her2-in-15.html