GZNL-P36 | MedChemExpress (MCE)

GZNL-P36 is an orally active inhibitor for SARS-CoV-2 papain-like protease (PL^pro), with an IC₅₀ of 6.45 nM. GZNL-P36 inhibits SARS-CoV and its variants with EC₅₀ range from 58.2 nM to 2.66 μM. GZNL-P36 exhibits a peak plasma concentration C_max of 549 ng/mL, a half-life T_1/2 of 1.45 h and a bioavailability of 74.7% in CD-1 mouse. GZNL-P36 exhibits antiviral activity in SARS-CoV-2 XXB.1 infection in mouse^[1].

Price Not Available 1 mg GZNL-P36 | MedChemExpress (MCE) Supplier Page

Trivial name	GZNL-P36
Catalog Number	HY-162484
Research Area	Infection
Purity	≥98.0%
SMILES	CN1C2=CC=C(C3(CC3)NC(C4=CC(N5CC(C6)N(C)C6C5)=CC=C4C)=O)C7=C2C(C1=O)=CC=C7
Size	1 mg
Supplier Page	https://www.medchemexpress.com/gznl-p36.html