FLT3/CHK1-IN-2 | MedChemExpress (MCE)
FLT3/CHK1-IN-2 (Compound 30) is a dual inhibitor of FLT3 and CHK1, with IC50s of 25.63, 16.39, 22.80 nM for CHK1, FLT3-WT, and FLT-D835Y respectively. FLT3/CHK1-IN-2 has favorable oral PK properties and kinase selectivity. FLT3/CHK1-IN-2 can be used for research of acute myeloid leukemia (AML)[1].
| Trivial name | FLT3/CHK1-IN-2 |
| Catalog Number | HY-162367 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | NCCCNC1=NC(NC2=CC(CCN(S(=O)(C)=O)C3)=C3C=C2)=NC=C1C(F)(F)F |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/flt3-chk1-in-2.html |