Cyclo(CRLLIF) | MedChemExpress (MCE)

Cyclo CRLLIF is a dual inhibitor for hypoxia inducible factor (HIF) 1 and 2, which disrupts the interaction of both HIF1-α and HIF2-α with HIF1-β, with affinity for HIF1-α and HIF2-α PAS-B domains KD of 14.5 and 10.2 μM, respectively[1].

Trivial name Cyclo(CRLLIF)
Catalog Number HY-P10222
Research Area Cancer
Purity ≥98.0%
SMILES O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H]1CC2=CC=CC=C2)=O)=O)=O)=O)[C@H](CS)NC1=O
Size 1 mg
Supplier Page https://www.medchemexpress.com/cyclo-crllif.html