cis-MZ 1 hydrate | MedChemExpress (MCE)
cis-MZ 1 hydrate is a negative control for BRD4-targeted PROTAC MZ 1 (HY-107425). cis-MZ 1 or MZ 1 is a combination of the von Hippel-Lindau ligand (red part in the structural formula) and the BRD4 ligand (blue part in the structural formula). The Kd of MZ 1 for BRD4 BD1/2 was 382 nM and 120 nM, respectively[1].
Trivial name | cis-MZ 1 hydrate |
Catalog Number | HY-107425B |
Research Area | Cancer |
Purity | ≥99.0% |
SMILES | CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@@H](C4)O)C(NCC5=CC=C(C6=C(N=CS6)C)C=C5)=O)=O)=O)=O)C7=NN=C(C)N27.[0.25].O |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/cis-mz-1-hydrate.html |