CBPD-409 | MedChemExpress (MCE)

CBPD-409 is an orally active PROTAC degrader for CBP/p300, with DC₅₀ of 0.2–0.4 nM. CBPD-409 exhibits antiproliferative effects in AR+ prostate cancer cell lines VCaP, LNCaP and 22Rv1, with IC₅₀s of 1.2–2.0 nM. CBPD-409 exhibits antitumor efficacy (Red: CBP inhibitor GNE049 (HY-108435); Blue: CRBN/cullin 4A Thalidomide (HY-14658); Black: Linker)^[1].

Price Not Available 1 mg CBPD-409 | MedChemExpress (MCE) Supplier Page

Trivial name	CBPD-409
Catalog Number	HY-158113
Research Area	Cancer
Purity	≥98.0%
SMILES	O=C(N1C2C(NC(CC2)=O)=O)C3=CC(N4CCN(C[C@@H]5CC[C@@H](N6C7=C(CN(C(C)=O)CC7)C(N8C9=C(CCC8)C=C(C(C(F)F)=C9)C%10=CN(C)N=C%10)=N6)CC5)CC4)=CC=C3C1=O
Size	1 mg
Supplier Page	https://www.medchemexpress.com/cbpd-409.html