BTX-6654 | MedChemExpress (MCE)
BTX-6654 is a target-dependent and -specific cereblon-based bifunctional SOS1 PROTAC degrader. BTX-6654 reduces downstream signaling markers pERK and pS6, and displays antiproliferative activity in cells harboring various KRAS mutations[1].
| Trivial name | BTX-6654 |
| Catalog Number | HY-161233 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | FC(F)(F)C1=C(C)C([C@@H](C)NC2=NN=C(C)C3=CC=C(N4CCN(C(C5CCN(C(CCN6CCC(C7=CC(CN(C8CCC(NC8=O)=O)C9=O)=C9C=C7F)CC6)=O)CC5)=O)CC4)C=C32)=CC=C1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/btx-6654.html |