Antiproliferative agent-49 | MedChemExpress (MCE)
Antiproliferative agent-49 (Compound 5a) is a EGFR-TK inhibitor with an IC50 of 0.09 μM. Antiproliferative agent-49 is a anti-proliferative agent. Antiproliferative agent-49 displays good activities against HER3 and HER4 with IC50 values 0.18 and 0.37 µM. Antiproliferative agent-49 induces mitochondrial apoptotic pathway and increased accumulation of ROS[1].
| Trivial name | Antiproliferative agent-49 |
| Catalog Number | HY-158016 |
| Research Area | Cancer |
| Purity | ≥98.0% |
| SMILES | C1(SCC2=CC=CC=C2)=NN=C(C3=CC=C(OCC4=CC=CC=C4)C=C3)O1 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/antiproliferative-agent-49.html |