Antileishmanial agent-27 | MedChemExpress (MCE)
Antileishmanial agent-27 (compound 7j) is a benzothiazolo-coumarin derivative. Antileishmanial agent-27 is a competitive inhibitor of arginyl-tRNA synthetases (ArgRSs). Antileishmanial agent-27 shows selectivity toward ArgRS of Leishmania donovani (LdArgRS) than its human counterpart (HsArgRS), with IC50 values of 1.2 and 19 μM, respectively. Antileishmanial agent-27 possesses high pharmacokinetic properties[1].
Trivial name | Antileishmanial agent-27 |
Catalog Number | HY-163457 |
Research Area | Infection |
Purity | ≥98.0% |
SMILES | O=C1OC2=CC(OCC3=CC=C(Br)C=C3)=CC=C2C(CSC4=NC5=C(S4)C=CC=C5)=C1 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/antileishmanial-agent-27.html |