α-Amylase/α-Glucosidase-IN-10 | MedChemExpress (MCE)
α-Amylase/α-Glucosidase-IN-10 (compound 5d) is an α-amylase and α-glucosidase inhibitor (IC50: 30.39 μM and 65.1 μM) with potential diabetes inhibitory effects. α-Amylase/α-Glucosidase-IN-10 exhibits high gastrointestinal (GI) absorption in ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) prediction. While α-Amylase/α-Glucosidase-IN-10 acts as a substrate for P-gp and does not cross the blood-brain barrier (BBB), there may be a risk of central nervous system side effects[1].
Trivial name | α-Amylase/α-Glucosidase-IN-10 |
Catalog Number | HY-162373 |
Research Area | Metabolic Disease |
Purity | ≥98.0% |
SMILES | O=C(/C1=N\NC(COC2=C(C)C=CC=C2C[C@H]3ON([C@]4(C[C@H](C)CC[C@H]4C(C)C)N(C)C5=O)[C@@]5([H])C3)=O)NC6=C1C=CC(Cl)=C6 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/α-amylase-α-glucosidase-in-10.html |