(1R,2R)-Calhex 231 hydrochloride | MedChemExpress (MCE)
(1R,2R)-Calhex 231 hydrochloride is the inactive isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment[1][2].
| Trivial name | (1R,2R)-Calhex 231 hydrochloride |
| Catalog Number | HY-103320B |
| Research Area | Metabolic Disease |
| Purity | 99.07% |
| SMILES | O=C(N[C@H]1[C@H](N[C@@H](C2=C3C=CC=CC3=CC=C2)C)CCCC1)C4=CC=C(Cl)C=C4.[H]Cl |
| PubChem Chemical Structure ID | 168510219 |
| Size | 10 mg |
| Supplier Page | https://www.medchemexpress.com/1r-2r-calhex-231-hydrochloride.html |