UK-5099
UK-5099 is a potent and specific inhibitor of MPC (mitochondrial pyruvate carrier) activity. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria with an IC₅₀ value of 50 nM. UK-5099 has recently been shown to block pyruvate from entering the mitochondria, which forces the production of lactate in the hair follicle stem cells and accelerates hair growth in mice.
| Trivial name | UK-5099 (RE1061) |
| Catalog Number | RE1061 |
| Alternative Name(s) | 2-cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid |
| Research Area | Other/Reagents |
| Molecular Formula | C₁₈H₁₂N₂O₂ |
| Inchi | InChI=1S/C18H12N2O2/c19-11-13(18(21)22)10-14-12-20(15-6-2-1-3-7-15)17-9-5-4-8-16(14)17/h1-10,12H,(H,21,22)/b13-10+ |
| Size | 10mg |
| Supplier Page | https://www.mitochondriasci.com/uk-5099-item-632.html |
| Additional Information | Appearance:Yellow solid |