Lonidamine
Lonidamine is a derivative of indazole-3-carboxylic acid that inhibits glycolysis by the inactivation of hexokinase, an enzyme that catalyzes glucose as the first step in glycolysis. Also blocks CFTR Cl- channels in vitro. Acts as an anticancer and antispermatogenic agent in vitro and in vivo.
| Trivial name | Lonidamine (RE1067) |
| Catalog Number | RE1067 |
| Alternative Name(s) | 1-[(2,4-Dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid |
| Research Area | Other/Reagents |
| Molecular Formula | C₁₅H₁₀Cl₂N₂O₂ |
| Inchi | InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21) |
| Size | 10mg |
| Supplier Page | https://www.mitochondriasci.com/lonidamine-item-638.html |
| Additional Information | Appearance:White solid |