JC-1 is a mitochondrial dye that stains mitochondria in Living cells in a membrane potential-dependent fashion. JC-1 monomer is in equilibrium with so-called J-aggregates, which are favored at higher mitochondrial membrane potential. The monomer JC-1 has green fluorescence (lem = 527 nm), while the J-aggregates have red fluorescence (lem = 590 nm). Therefore, it has been possible to use a fluorescence rationing technique to study mitochondrial membrane potential. JC-1 is particularly useful for apoptosis studies. In apoptotic cells, the dye stays in the cytoplasm and fluoresces green, while in healthy cells, the dye aggregates in the mitochondria and fluoresces red.

Price Not Available 10mg JC-1 Supplier Page
Trivial name JC-1 (RE1065)
Catalog Number RE1065
Alternative Name(s) 5,5’,6,6’-tetrachloro-1,1’,3,3’-tetraethyl-benzimidazolylcarbocyanine Iodide
Research Area Other/Reagents
Molecular Formula C₂₅H₂₇Cl₄IN₄
Inchi InChI=1S/C25H27Cl4N4.HI/c1-5-30-20-12-16(26)17(27)13-21(20)31(6-2)24(30)10-9-11-25-32(7-3)22-14-18(28)19(29)15-23(22)33(25)8-4;/h9-15H,5-8H2,1-4H3;1H/q+1;/p-1
Size 10mg
Supplier Page https://www.mitochondriasci.com/jc-1-item-636.html
Additional Information Appearance:Brown red solid