Artesunate
Artesunate is a semisynthetic derivative of artemisinin. It acts on the electron transport chain, generates local reactive oxygen species, and causes the depolarization of the mitochondrial membrane. It inhibits TNFα-induced production of proinflammatory cytokines via inhibition of NF-κB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.
| Trivial name | Artesunate (RE1009) |
| Catalog Number | RE1009 |
| Alternative Name(s) | WR-256283; NSC-712571; Artesunic acid; butanedioic acid, 1-[(3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester |
| Research Area | Other/Reagents |
| Molecular Formula | C₁₉H₂₈O₈ |
| Inchi | InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18-,19-/m1/s1 |
| Size | 10mg |
| Supplier Page | https://www.mitochondriasci.com/artesunate-item-580.html |
| Additional Information | Appearance:White to off-white solid |