Difloxacin is a?quinolone?that is?pefloxacin?in which the ethyl group at position 1 of the?quinolone?has been replaced by a p-fluorophenyl group. A broad-spectrum antibiotic effective against both Gram-positive and Gram-negative bacteria, it is used (usually as the?monohydrochloride?salt) for the treatment of bacterial infections in dogs. It has a role as an antibacterial drug and a Mycoplasma genitalium metabolite. It is a?quinolone, a N-alkylpiperazine, a N-arylpiperazine, a?quinolone?antibiotic, a?fluoroquinolone?antibiotic, a member of monofluorobenzenes and a monocarboxylic acid.