PROTAC KRAS G12C degrader-1| ChemScene
PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C PROTAC degrader. PROTAC KRAS G12C degrader-1 induces CRBN/ KRASG12C dimerization and degrades GFP- KRASG12C in reporter cells.In Vitro:PROTAC KRAS G12C degrader-1 (Compound 10) engages CRBN in cells, bound KRASG12C in vitro, induces CRBN/KRASG12C dimerization, and degrades GFP-KRASG12C in reporter cells in a CRBN-dependent manner.
| Trivial name | PROTAC KRAS G12C degrader-1 |
| Catalog Number | CS-0181600 |
| Molecular Formula | 917.47 |
| Purity | >98% |
| Condensed Formula | C50H54ClFN8O6 |
| Size | 25mg |
| Supplier Page | www.chemscene.com/CS-0181600.html |