(Z-IETD)2-Rh 110 (trifluoroacetate salt)

A fluorogenic substrate for caspase-8

Catalog Number 28212
Alternative Name(s) (Z-Ile-Glu-Thr-Asp)2-R110|Rhodamine 110 bis-(N-CBZ-IETD)2
Research Area Apoptosis|Cell Biology|Cell Death|Cytosolic & Secreted Proteases|Proteolysis
Molecular Formula C74H86N10O25 • XCF3COOH
Purity ≥95%
Inchi InChI=1S/C74H86N10O25.C2HF3O2/c1-7-37(3)59(83-72(104)106-35-41-17-11-9-12-18-41)67(99)77-49(27-29-55(87)88)63(95)81-61(39(5)85)69(101)79-51(33-57(91)92)65(97)75-43-23-25-47-53(31-43)108-54-32-44(24-26-48(54)74(47)46-22-16-15-21-45(46)71(103)109-74)76-66(98)52(34-58(93)94)80-70(102)62(40(6)86)82-64(96)50(28-30-56(89)90)78-68(100)60(38(4)8-2)84-73(105)107-36-42-19-13-10-14-20-42;3-2(4,5)1(6)7/h9-26,31-32,37-40,49-52,59-62,85-86H,7-8,27-30,33-36H2,1-6H3,(H,75,97)(H,76,98)(H,77,99)(H,78,100)(H,79,101)(H,80,102)(H,81,95)(H,82,96)(H,83,104)(H,84,105)(H,87,88)(H,89,90)(H,91,92)(H,93,94);(H,6,7)/t37-,38-,39+,40+,49-,50-,51-,52-,59-,60-,61-,62-;/m0./s1
Inchi Key UUTKUGGZGIYRMX-REXNWUKNSA-N
SMILES OC(C[C@H](NC([C@](NC([C@@H](NC([C@@]([C@@H](C)CC)([H])NC(OCC1=CC=CC=C1)=O)=O)CCC(O)=O)=O)([H])[C@@H](C)O)=O)C(NC2=CC=C(C3(C(C=CC=C4)=C4C(O3)=O)C(C=CC(NC([C@H](CC(O)=O)NC([C@@](NC([C@H](CCC(O)=O)NC([C@]([C@H](CC)C)(NC(OCC5=CC=CC=C5)=O)[H])=O)=O)([C@H](O)C)[H])=O)=O)=C6)=C6O7)C7=C2)=O)=O.FC(F)(C(O)=O)F
Size 1 mg
Supplier Page https://www.caymanchem.com/product/28212