AMG 18 (hydrochloride)
An IRE1α inhibitor
| Catalog Number | 43488 |
| Alternative Name(s) | Kinase-inhibiting RNase Attenuator 8|KIRA8 |
| Research Area | Product Type|Small Molecule Modulators|Small Molecule Inhibitors||Research Area|Cancer||Research Area|Cell Biology|ECM & Adhesion Molecules||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|ER Protein Folding||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Steatotic Liver Diseases||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|RSV Infections |
| Molecular Formula | C31H29ClN6O3S • XHCl |
| Purity | ≥98% |
| Inchi | InChI=1S/C31H29ClN6O3S.ClH/c1-20-13-14-22-23(8-4-11-27(22)38-42(39,40)28-12-3-2-10-25(28)32)29(20)41-30-24(9-6-17-34-30)26-15-18-35-31(37-26)36-21-7-5-16-33-19-21;/h2-4,6,8-15,17-18,21,33,38H,5,7,16,19H2,1H3,(H,35,36,37);1H/t21-;/m0./s1 |
| Inchi Key | CNWIPRHGMZTPSB-BOXHHOBZSA-N |
| SMILES | CC(C=C1)=C(OC2=C(C3=NC(N[C@@H]4CNCCC4)=NC=C3)C=CC=N2)C5=C1C(NS(C6=C(Cl)C=CC=C6)(=O)=O)=CC=C5.Cl |
| Size | 5 mg |
| Supplier Page | https://www.caymanchem.com/product/43488 |